Origin of variability in quantal size in cultured hippocampal neurons and hippocampal slices.

نویسندگان
چکیده

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Effects of resveratrol on intrinsic neuronal properties of CA1 pyramidal neurons in rat hippocampal slices

Introduction: Resveratrol (3,5,4-trihydroxystilbene) a non-flavonoid polyphenol found in some plants like grapes, peanuts and pomegranates, possesses a wide range of biological effects. Evidence indicates that resveratrol has beneficial effects on nervous system to induce neuroprotection. However, the cellular mechanisms of the effects are not fully determined. In the present study, the cellula...

متن کامل

Electrophysiological characteristics of hippocampal CA1 neurons after spreading depression-triggered epileptic activity in brain slices

Introduction: A close link between spreading depression (SD) and several neurological diseases such as epilepsy could be demonstrated in many experimental studies. Epilepsy is among the most common brain disorders. Despite a large number of investigations, its mechanisms have not been yet well elucidated. Hippocampus is one of the important structures involved in seizures. The aim of this st...

متن کامل

Channels in Cultured Hippocampal Neurons

As the Ca 2 -sensor for Ca 2 -dependent inactivation, calmodulin (CaM) has been proposed, but never definitively demonstrated, to be a constitutive CaV1.2 Ca 2 channel subunit. Here we show that CaM is associated with the CaV1.2 pore-forming 1C subunit in brain in a Ca 2 -independent manner. Within its CaM binding pocket, 1C has been proposed to contain a membrane targeting domain. Because ion ...

متن کامل

Oscillations of Cultured Hippocampal Neurons

Ginsenoside Rg1, the main active ingredient of Ginseng Radix which is a famous Chinese medicine, is widely used as an anti-stress, anti-aging and neurological performance improving agent. In this study, we used calcium imaging and whole-cell patch clamp techniques to investigate the effect of Ginsenoside Rg1 on spontaneous and synchronous Ca 2+ oscillations and the possible mechanisms in primar...

متن کامل

Dendritic spine density and LTP induction in cultured hippocampal slices.

Transverse hippocampal slices were cut from 8- to 9-day-old rats and maintained in an interface chamber for periods of 1-4 wk, in tissue culture conditions. Neurons in the slice preserved their spatial organization and connectivity. Dendritic spine density in CA1 neurons was very low at 1 wk in culture, and long, filopodia-like structures were abundant. Spine density increased in these neurons ...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Proceedings of the National Academy of Sciences

سال: 1990

ISSN: 0027-8424,1091-6490

DOI: 10.1073/pnas.87.14.5359